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Biomedical research gives scientists the platform to create sophisticated new drugs that will act with great precision. Research into monoclonal antibodies - discovered in Cambridge by George Kohler and Cesar Milstein - has revolutionised treatments for cancer. These are the so-called 'next generation' treatments for life-threatening conditions. An explosion in understanding of the molecular circuits controlling normal and diseased cells has identified many potential targets for the latest medicines. A multidisciplinary initiative, the Cambridge Molecular Therapeutics Programme (CMTP), directed by Professors Ashok Venkitaraman and Tom Blundell, seeks to pioneer methods for the discovery and development of next-generation drugs. CMTP brings together expertise in physical, chemical and biomedical sciences to develop novel approaches to drug discovery. The programme welcomes partnerships with commercial collaborators.


Professor Sharon Peacock

Department of Pathology and Department of Medicine
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Professor Peacock’s research focuses on the role of sequencing technologies in diagnostic microbiology and public health. She chairs the Cambridge Infectious Diseases Initiative and is deputy director of the newly awarded Wellcome Trust Cambridge Centre for Global Health Research. She was elected to the Academy of Medical Sciences in 2013.

Links with India

Prof Peacock organized a three-day workshop on infectious disease at the Indian Institute of Science, in partnership with the St John’s Research Institute, Bangalore in January 2014. The workshop, which was funded by the India-UK Scientific Seminar award, is expected to help initiate a number of longer-term research links between the three partner institutions.

Professor Ashok Venkitaraman

Medical Research Council's Cancer Cell Unit
Pembroke College
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Human cancer cells almost always contain abnormal chromosomes, yet the connections between chromosomal instability and carcinogenesis are poorly understood. Professor Venkitaraman's research aims not only at understanding how cells maintain normal chromosome structure and number and why maintenance breaks down in cancer cells, but also to translate this knowledge to improvements in cancer diagnosis and treatment. With Professor Sir Tom Blundell, he has established the Cambridge Molecular Therapeutics Programme (CMTP).

Links with India

Professor Venkitaraman was instrumental in setting up the Centre for Chemical Biology and Therapeutics (CCBT), and serves as the Centre's Adjunct Director. CCBT is located in Bangalore at the Institute for Stem Cell Biology and Regenerative Medicine (InStem), and was established in collaboration with the National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research following a INR940 million (approximately £11 million) grant from the Department of Biotechnology in 2012.

Professor Sir Tom Blundell FRS FMedSci

Department of Biochemistry
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Professor Blundell's research is focused on structural biology of cell regulation, structural bioinformatics and applications to drug discovery and medicine. He co-founded Astex Therapeutics which has oncology drugs in early stage clinical trials in USA and UK. He was Chairman of the Royal Commission on Environmental Pollution (1998 to 2005) and President of the UK Biosciences Federation between 2004 and 2008. He is non-executive Chairman of BBSRC.

Links with India

Professor Blundell's collaborations with Indian scientists include those with Professor M Vijayan and N Srinivasan at Indian Institute for Science (IISc), Bangalore; Dr R Sowdhamini at National Centre for Biological Sciences Bangalore; and Dr K Guruprasad at Centre for Cellular and Molecular Biology in Hyderabad; working with Astra Zeneca India through EU collaboration on drug discovery for TB; in 2008, Professor Blundell gave the Ramaseshan lecture at AstraZeneca India Pvt Ltd., he was Ramachandran Professor at IISc and gave the Ramalingaswami Memorial Lecture at the Jawaharlal Nehru Centre for Advanced Scientific Research, as well as lecturing at the University of Madras, Amrita University and Madurai Kamaraj University.

Professor Blundell is a Fellow of the Indian National Science Academy and the Third World Academy of Sciences.

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